NSAIDS may be more effective than acetaminophen for dysmenorrhea.
The Los Angeles Times (1/20, Dennis) "Booster Shots" blog reported that investigators at the Cochrane Library analyzed studies "on pain relief for dysmenorrhea," concluding that "non-steroidal anti-inflammatory drugs (NSAIDs) seem to be more effective at controlling such pain than paracetamol, known by most North Americans as acetaminophen."
Medscape (1/20, Barclay) reported that the study, based "on 73 randomized controlled trials meeting selection criteria," also found that "NSAIDs were significantly more effective for pain relief than placebo among women with primary dysmenorrhea," but were also "associated with significantly more overall adverse effects than placebo." In addition, the comparison "of various NSAIDs vs. other NSAIDs showed limited evidence that any individual NSAID was superior for either pain relief or safety."
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